Duane Brandau, D.O., Ph.D.,
Associate Professor of Biochemistry

Dr. Brandau came to Rocky Vista University from Children’s Mercy Hospitals and Clinics in Kansas City Missouri, where he worked as a research scientist in the Department of Medical Genetics and Molecular Medicine. His research focused on metabolic problems and the long-term outcomes of patients with Prader-Willi syndrome, the most common cause of syndromic obesity. While at Children’s Mercy Hospital, Dr. Brandau was also an Associate Professor of Pediatrics at the University of Missouri Kansas City School of Medicine. Dr. Brandau has a long career in osteopathic medical education including faculty appointments in Pediatrics and Biochemistry at both the Kirksville College of Osteopathic Medicine and the Kansas City University of Medicine and Biosciences. He has also served as the Vice Dean of Academic Affairs at both osteopathic colleges before returning to research at the University of Kansas in the Department of Pharmaceutical Chemistry. At the University of Kansas, Dr. Brandau was the Associate Director of the Macromolecule and Vaccine Stabilization Laboratory which specializes in the pre-formulation stability of pharmaceutically interesting macromolecules and vaccines.
Dr. Brandau graduated with his D.O. degree from Des Moines University in 1978, and a Ph.D. in biochemistry from the University of Wyoming in 1986.

Selected Publucations
Heun L, Brandau DT, Chi X, Wang P, Kangas J. A validation study of computer- mediated open-ended standardized patient assessments. Int J Med Inf.1998;50:235-241.

Brandau DT, Jones LTS, Wiethoff CM, Rexroad J, Middaugh CR. The thermal stability of vaccines. J Pharm Sci 2003;92:218-231.

Jiang G, Joshi SB, Peek, LJ, Brandau, DT, Huang J, Ferriter MS, Woodley WD, Ford BM, Mar KD, Mikszta JA, Hwang CR, Ulrich R, Harvey NG, Middaugh CR, Sullivan VJ. Anthrax vaccine powder formulations for nasal mucosal delivery. J Pharm Sci. 2006;95:80-96.

Driver LJ, Brandau DT, Jones LS, Joshi JB, and Middaugh CR. A systematic approach to stabilizing EBA-175 RII-NG for use as a malaria vaccine. Vaccine 2006;24(31- 32):5839-5851.

Lucas LH, Ersoy BA, Kueltzo LA, Joshi SB, Brandau DT, Thyagarajapuram N, Peek LJ, Middaugh CR. Probing protein structure and dynamics by second-derivative ultraviolet absorption analysis of cation-? Interactions. Protein Sci. 2006;15(20) 2228-2243.

Brandau DT, Joshi JB, Smalter AM, Kim S, Steadman B, Middaugh CR. Stability of the Clostridium botulinum type A neurotoxin complex; An empirical phase diagram based approach. Molecular Pharmaceutics 2007; 4(4) 571-582.

Brandau DT, Lund M, Cooley LD, Sanger WG, Butler MG. Autistic and dysmorphic features associated with a submicroscopic 2q33.3-q34 interstitial deletion detected by array comparative genomic hybridization. Am J Med Genet A. 2008;146(4) 521-524.

Brandau DT, Theodoro M, Garg U, Butler MG. Follicle stimulating and leutinizing hormones, estradiol and testosterone in Prader-Willi syndrome. Am J Med Genet A. 2008;146(5) 665-669.